Host genetic susceptibility to severe dengue infection

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Host genetic susceptibility to severe dengue infection

Epidemiological evidence indicates that host genetic factors are relevant and predispose DHF/DSS development. Here, we review the host genetic studies concerning human leucocyte antigens, antibody receptors, immune/inflammatory mediators, attachment molecules, cytokines and other factors exerting an immunoregulatory effect as well as the current genome-wide association studies. We also discuss ...

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ژورنال

عنوان ژورنال: Tropical Medicine and Health

سال: 2011

ISSN: 1349-4147,1348-8945

DOI: 10.2149/tmh.2011-s08